Dr Denovan Begg

Dr Denovan Begg

Dr Denovan Begg

Senior Lecturer and DECRA Fellow

B.B.Sc. (Hons.) La Trobe University, 2003
M.B.Sc. La Trobe University, 2008
Ph.D. Deakin University, 2011

Contact details

Phone: (02) 9385 2441
Email: Dr Denovan Begg
Fax: (02) 9385 3641

Office: Mathews, Room 708

Research Summary

Research Areas: 

Our lab primarily focuses on the regulation of ingestive behaviour by the central nervous system.


Psychology Honours Coordinator

PSYC1011 - Psychology 1B - Psychobiology component

PSYC4103 - Psychology 4B -  Elective - The Neurobiology of Obesity

NEUR4411- Behavioural Neuroscience


Recent Publications:

Ip CK, Zhang L, Farzi A, Clarke I, Reed F, Shi Y-C, Enriquez R, Qi Y, Dayas C, Graham B, Begg DP, Brüning JC, Hernandez-Sanchez D, Tasan R, Sperk G and Herzog H. Amygdala NPY circuits promote the development of obesity under chronic stress conditions. Cell Metabolism. pii: S1550-4131(19)30185-8. doi: 10.1016/j.cmet.2019.04.001, 2019.

Goulter N, Kimonis ER, Denson TF, Begg DP. Female primary and secondary psychopathic variants show distinct endocrine and psychophysiological profiles. Psychoneuroendocrinology. 104:7-17, 2019.

Gladding JM, Abbott KN, Antoniadis CP, Stuart A, Begg DP. The Effect of Intrahippocampal Insulin Infusion on Spatial Cognitive Function and Markers of Neuroinflammation in Diet-induced Obesity. Front Endocrinol. 9:752, 2018.

Woods SC, May-Zhang AA, Begg DP. How and why do gastrointestinal peptides influence food intake? Physiol Behav. 193:218-222, 2018.

Loh K, Zhang L, Brandon A, Wang Q, Begg D, Qi Y, Fu M, Kulkarni R, Teo J, Baldock P, Brüning JC, Cooney G, Neely GG, Herzog H. Insulin controls food intake and energy balance via NPY neurons. Mol Metab. 6(6):574-584, 2017.
Begg DP. Disturbances of thirst and fluid balance associated with aging. Physiol Behav. 178:28-34, 2017.

Woods SC, May AA, Liu M, Tso P, Begg DP. Using the cerebrospinal fluid to understand ingestive behavior. Physiol Behav. 178:172-178, 2017.

Woods SC, Begg DP. Regulation of the Motivation to Eat. Curr Top Behav Neurosci. 27:15-34, 2016.

May AA, Liu M, Woods SC, Begg DP. CCK increases the transport of insulin into the brain. Physiol Behav. 165:392-7, 2016.

To access all of my publications, please view my UNSW Research Gateway profile.

Awards, Fellowships & Grants

2011-2016: National Health and Medical Research Council Early Career Fellowship. The renin-angiotensin system and obesity. $309,816. Begg.

2014-2016: Ramaciotti Foundations Establishment Grant. Identifying the mechanisms that reduce hypertension following weight-loss surgery. $75,000. Begg.

2015 UNSW Science Silverstar Grant. Central nervous system insulin and leptin transport and resistance in obesity. $35,000. Begg.

2016-2019 Australian Research Council: Discovery Early Career Researcher Award. Central nervous system insulin and hippocampal-dependent cognitive function $390,000. Begg.

2016 UNSW Science Silverstar Grant. The cyclooxygenase-eicosanoid pathway and fatty acids alter thirst in aging. $35,000. Begg.

2016 Diabetes Australia Research Trust. Central nervous system insulin transport and resistance in obesity. $59,860. Begg.

2017-2019 Australian Research Council: Discovery Project. The mechanisms of insulin transport into the central nervous system $342,000. Begg and Herzog.

2019-2021 National Health and Medical Research Council: Project Grant. Central nervous system insulin transport and bariatric surgery $432,127. Begg, Smith and Grattan.

2019-2022 National Health and Medical Research Council: Project Grant. The pursuit to develop mechanism-based interventions for polycystic ovary syndrome (PCOS) $756,560. Walters, Handelsman, Campbell, Anderson, Gilchrist, Padmanaban and Begg.

Affiliations & Memberships

Australasian Neuroscience Society

Society for Neuroscience 

Australian and New Zealand Obesity Society

Society for the Study of Ingestive Behavior

Nutrition Society of Australia

Current Research Students

Elisabeth Goodman

Kirsten Abbott

Neda Rafiei

Joanne Gladding