Dr Sylvia M Gustin

Dr Sylvia M Gustin

Dr Sylvia M Gustin

Senior Research Fellow

Gustin Pain Imaging Laboratory (www.gustinpil.com)

EDUCATION

1997; Bachelor in Psychology, School of Psychology, University of Tubingen, Germany

2002; Master in Psychology, Department of Clinical Psychology & Psychotherapy, School of Psychology, University of Tubingen, Germany; Master thesis: Hemispheric differences in pre- and post-operative testing, between neuropsychological factors and magnetically evoked fields in patients with space-occupation close to the central sulcus; Supervisor: Prof. Niels Birbaumer

2006; PhD in Psychology, Department of Clinical Psychology & Psychotherapy, School of Psychology, University of Tubingen, Germany; Doctoral thesis: Therapy-induced cortical reorganization and analgesia in patients with neuropathic pain – a fMRI and MEG study; Supervisor: Prof. Niels Birbaumer

RESEARCH AND WORK

1997-1998; Research Associate; Project: The role of operant conditioning in the development of chronic low back pain, Institute of Medical Psychology & Behavioural Neurobiology, University of Tubingen, Germany

1998-1999; Research Associate; Project: Neuropsychological testing in patients after unilateral parietal and premotor lesions, School of Psychology, Department of Neuropsychology, University of Freiburg, Germany

1999-2001; Research Associate; Project: Cortical reorganization after amputation in humans, Institute of Medical Psychology & Behavioural Neurobiology, University of Tubingen, Germany

1999-2001; Training as Hypnotherapist, Milton Erickson Institute for Hypnotherapy, Germany

2002-2006; Research Fellow; Project 1: Effects on cortical organization and psychological variables in patients with complex regional pain syndrome (CRPS), when the NMDA-receptor antagonist is combined with morphine; project 2: Cortical reorganization in patients with CRPS: Effect of a somatosensory training, Institute of Medical Psychology & Behavioural Neurobiology, University of Tubingen, Germany

2002-2006; Associate Lecturer for undergraduate/graduate students in Neural & Behavioural Sciences, Institute of Medical Psychology & Behavioural Neurobiology, University of Tuebingen, Germany

2002; Clinical Placement at the German Red Cross Centre, Mainz, Germany

2003; Clinical Placement at the Pain Management & Research Centre, Royal North Shore Hospital,  Sydney, Australia

2003-2006; Psychologist (part-time) at the International Vocational Training Centre, Stuttgart, Germany. Role: Psychological assessment, psychological diagnosis and cognitive behavioural therapy and treatment with students with behavioural, cognitive or social challenges between 15-30 years

2007-2009; Postdoctoral Researcher, Project 1: psychological factors and brain alterations underlying orofacial pain, Faculty of Dentistry, University of Sydney; project 2: psychological factors and brain mechanisms underlying neuropathic pain following spinal cord injury, Pain Management Research Institute, University of Sydney, Australia

2007-2014; Lecturer for Neuroscience Seminar Series for senior students (Integrative Neuroscience NEUR3004, NEUR3904), Department of Anatomy & Histology, University of Sydney, Australia

2009-2014; Career Development Fellow (NSW Spinal Cord Injury and Related Neurological Conditions Research Grant Program), Project: Examination into the long-term clinical effectiveness of transcranial direct current stimulation in patients with neuropathic pain following spinal cord injury, Pain Management Research Institute and Department of Anatomy & Histology, University of Sydney, Australia

2014; Lecturer for Social Psychology (PSYC313) at the national School of Psychology, Faculty of Health Sciences, Australian Catholic University (ACU)

2015; Senior Research Fellow, Gustin Pain Imaging Laboratory, School of Psychology, University of New South Wales, Australia

Contact details

Phone: (02) 9399 1894
Email: Dr Sylvia M Gustin

Office: Room 2.06

Research Summary

For the past 20 years I have been using brain imaging techniques and psychological assessment to investigate the central and psychological circuits underlying chronic pain in humans. I have experience in the use of many brain imaging techniques such as magnetoencephalography and functional, structural and biochemical magnetic resonance imaging. In addition, I have practised as a psychologist focusing on the management of chronic pain. My aim is to increase our understanding of the development and maintenance of chronic pain, in particular psychological and central components and their association with each other.

Read more about my research here: What Are The Causes Of Chronic Pain? Is It All In The Mind?

Publications

Wilcox S.L., GustinS.M., MaceyP.M., Peck C.C., Murray G.M., Henderson L.A. (2015) Anatomical changes within the medullary dorsal horn in chronic temporomandibular disorder pain. Neuroimage, doi: 10.1016/j.neuroimage.2015.05.014

Gustin S.M., Burke L., Peck C.C., Murray G.M., and Henderson L.A. (2015) Pain and Personality: Do individuals with different forms of chronic pain exhibit a mutual personality? Pain Practice, doi: 10.1111/papr.12297.

Wilcox S., Gustin S.M., Macey P., Peck C.C., Murray G.M., and Henderson L.A. (2015) Anatomical changes at the level of the primary synapse in neuropathic pain: evidence from the spinal trigeminal nucleus. Journal of Neuroscience, 11;35(6):2508-15.

Gustin, S.M., Peck, C.C., Cheney, L., Murray, G.M. and Henderson, L.A. Pain and Plasticity: Is chronic pain always associated with somatosensory cortex activity and reorganization? Journal of Neuroscience, 32(43): 14874-14884.

Gustin, S.M., Wrigley,P.J., Youssef,A.M., McIndoe,L., Wilcox,S., Rae,C.D., Edden,R., Siddall,P.J., Henderson,L.A. (2014) Thalamic activity and biochemical changes in individuals with neuropathic pain following spinal cord injury. Pain, 155(5): 1027-36.

Youssef A.M., Gustin S.M., Nash PJ, Reeves J.M., Petersen E.T., Peck C.C., Murray G.M. and Henderson L.A. (2014) Differential brain activity in subjects with painful trigeminal neuropathy and painful temporomandibular disorder. Pain, 155(3): 467-75.

Gustin, S.M., Peck, C., Macey, P.M., Murray, G.M.and Henderson, L.A. (2013) Unraveling the effects of plasticity and pain on personality. Journal of Pain, 14:1642-1652

Wrigley, P.J., Gustin, S.M., McIndoe, L. Chakiath, R.J., Henderson, L.A. and Siddall, P.J. (2013) Long standing neuropathic pain following spinal cord injury is refractory to transcranial direct current stimulation: a randomized controlled trial. Pain, 154: 2178-2184.

Henderson, L.A., Peck, C.C., Petersen, E.T., Rae, C., Youssef, A., Reeves, J., Wilcox S.L., Akhter, R., Murray, G.M. and Gustin, S.M. Chronic pain - lost inhibition? Journal of Neuroscience, 33(17):7574-82.

Wilcox, S.L., Gustin, S.M., Eykman, E.N., Fowler, G., Peck, C.C., Murray, G.M. and Henderson, L.A. (2013) Trigeminal nerve anatomy in neuropathic and non-neuropathic orofacial pain patients. Journal of Pain, 14(8):865-72.

Gustin, S.M., Peck, C.C., Cheney, L., Murray, G.M. and Henderson, L.A. Pain and Plasticity: Is chronic pain always associated with somatosensory cortex activity and reorganization? Journal of Neuroscience, 32(43): 14874-14884.

Gustin, S.M., Peck, C.C., Wilcox, S.L., Nash, P.G, Murray, G.M. and Henderson, L.A. (2011). Different pain, different brain: thalamic anatomy in neuropathic and non-neuropathic chronic pain syndromes.  Journal of Neuroscience, 31(16): 5956 - 64.

Gustin, S.M., Wilcox, S.L., Peck, C.C., Murray, G.M. and Henderson L.A. (2011). Similarity of suffering: equivalence of psychological and psychosocial factors in neuropathic and non-neuropathic orofacial pain patients.  Pain, 152(4): 825 – 832.

Henderson, L.A., Gustin, S.M., Macey, P.M., Wrigley, P.J. and Siddall, P.J. (2011). Functional reorganization of the brain in humans following spinal cord injury: Evidence for underlying changes in cortical anatomy.  Journal of Neuroscience, 31(7): 2630 – 2637.

Gustin, S.M., Schwarz, A., Birbaumer, N., Sines, N., Schmidt, A.C., Veit, R., Larbig, W., Flor, H. and Lotze, M. (2010). NMDA-receptor antagonist and morphine decrease CRPS-pain and cerebral pain representation.  Pain, 148(3): 438 – 445.

Nash, P.G., Macefield, V.G., Klineberg, I.J., Gustin, S.M., Murray, G.M. and Henderson, L.A. (2010). Changes in human primary motor cortex activity during acute cutaneous and muscle orofacial pain.  Journal of Orofacial Pain, 24(3): 379 – 390.

Gustin, S.M., Wrigley, P.J., Henderson, L.A. and Siddall, P.J. (2010). Brain circuitry underlying pain in response to imagined movement in people with spinal cord injury.  Pain, 14 (3): 438 – 445.

Gustin, S.M., Wrigley, P.J., Siddall, P.J. and Henderson, L.A. (2010). Brain anatomy changes associated with persistent neuropathic pain following spinal cord injury. Cerebral Cortex, 20(6): 1409–19.

Nash, P.G., Macefield, V.G., Klineberg, I.J., Gustin, S.M., Murray, G.M. and Henderson, L.A. (2010). Bilateral activation of the trigeminothalamic tract by acute orofacial cutaneous and muscle pain in humans.  Pain, 151(2): 384 - 393.

Wrigley, P.J., Press, S.R., Gustin, S.M., Macefield, V.G., Gandevia, S.C., Cousins, M.J., Middleton, J.W., Henderson, L.A. and Siddall, P.J. (2009). Neuropathic pain and primary somatosensory cortex reorganization following spinal cord injury.  Pain, 141: 52 -59.

Wrigley, P., Gustin, S.M., Macey, P.M, Macefield, V.G., Gandevia, S.C., Siddall, P.J. and Henderson, LA. Anatomical changes in human motor cortex and motor pathways following complete thoracic spinal cord injury  Cerebral Cortex  (2009)  19(1): 224 – 232.

Gustin, S.M., Wrigley, P.J., Gandevia, S.C., Middleton, J.W., Henderson, L.A. and Siddall, P.J. (2008). Movement imagery evokes pain in people with neuropathic pain following complete thoracic spinal cord injury.  Pain, 137(2): 237 – 244.

Sinis, N., Birbaumer, N., Gustin, S.M., Schwarz, A., Bredanger, S., Becker, S.T., Unertl, K., Schaller, H.E. and Haerle, M. (2007). Memantine Treatment of Complex Regional Pain Syndrome: a preliminary report of six cases.  Clin J Pain, 23(3):  237 – 243.

Sinis, N., Birbaumer, N., Schwarz, A., Gustin, S.M., Unertl, K., Schaller, H.E. and Haerle, M. (2006). Memantine and Complex Regional Pain Syndrome (CRPS): Effects of Treatment and Cortical Reorganisation. Handchir Mikrochir Plast Chir, 38: 164 - 171.

Schumann, G., Halsband, U., Kassubek, J., Gustin S.M., Heinks, T., Juengling, F.D. and Hüll M. (2000). Combined semantic dementia and apraxia in a patient with frontotemporal lobar degeneration.  Psychiatry Res, 100(1): 21 -29.

Book chapters published

Gustin, S.M., Wilcox, S.L. and Henderson, L.A. (2012). Does every pain have its own psychology? A review of psychosocial components in chronic pain of different aetiologies in “Advances in Psychology Research”, Volume 95, Nova Science Publishers.

Awards, Fellowships & Grants

2005; Research fellowship, German Academic Exchange Service  (7,502 Euro)

2005; Co-investigator BMBF project grant; Cortical reorganization in patients with complex regional pain syndrome: Effect of a somatosensory training, Institute of Medical Psychology & Behavioural Neurobiology, University of Tubingen, Germany  (207,876 Euro)

2009; Career Developmental Fellowship, NSW Spinal Cord Injury and Related Neurological Conditions Research Grant Program  (580,783 A$)

2010; Early Career Researcher Grant, University of Sydney, Australia (22,000 A$)

2013; Mackintosh Grant, University of Sydney, Australia  (15,000 A$)

2014; Bridging Grant, University of Sydney, Australia  (30,000 A$)

2015; CIA NHMRC project grant; Identifying the neural signature of persistent pain, School of Psychology, University of New South Wales, Australia  (530,105 A$)

2016; AI & Val Rosenstrauss Fellowship, Rebecca L. Cooper Medical Research Foundation (400,000 A$)

Affiliations & Memberships

Registered Psychologist with the Psychological Board of Australia

Personal Links

http://www.gustinpil.com/